Satheesh Chonat Selected Research

Pyruvate Kinase Deficiency of Red Cells

1/2022	Mitapivat versus Placebo for Pyruvate Kinase Deficiency.
4/2021	Comorbidities and complications in adults with pyruvate kinase deficiency.
1/2021	Pyruvate kinase deficiency in children.
1/2021	The pyruvate kinase (PK) to hexokinase enzyme activity ratio and erythrocyte PK protein level in the diagnosis and phenotype of PK deficiency.
1/2020	Genotype-phenotype correlation and molecular heterogeneity in pyruvate kinase deficiency.
1/2018	Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study.
1/2018	Alu element insertion in PKLR gene as a novel cause of pyruvate kinase deficiency in Middle Eastern patients.

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Satheesh Chonat Research Topics

Disease

8	Hemolytic Anemia 01/2022 - 01/2018
7	Pyruvate Kinase Deficiency of Red Cells 01/2022 - 01/2018
4	Hemolysis 01/2022 - 11/2020
4	Thrombosis (Thrombus) 01/2022 - 01/2021
4	Infections 01/2022 - 01/2018
4	Sickle Cell Anemia (Hemoglobin S Disease) 12/2020 - 11/2016
3	Anemia 01/2022 - 01/2019
3	Pulmonary Hypertension 04/2021 - 01/2020
3	Transfusion Reaction 10/2019 - 11/2018
2	Paroxysmal Hemoglobinuria (Paroxysmal Nocturnal Hemoglobinuria) 01/2022 - 01/2022
2	Thrombotic Microangiopathies 11/2021 - 12/2020
2	Inflammation (Inflammations) 10/2021 - 01/2018
2	COVID-19 01/2021 - 01/2020
2	Iron Overload 01/2020 - 01/2018
2	Congenital Hemolytic Anemia (Hemolytic Anemia, Congenital) 01/2020 - 01/2018
1	Neoplasms (Cancer) 01/2022
1	Bone Marrow Failure Disorders 01/2022
1	Chronic Disease (Chronic Diseases) 01/2022
1	Fatigue 01/2022
1	Headache (Headaches) 01/2022
1	Nausea 01/2022
1	Viremia 10/2021
1	Critical Illness (Critically Ill) 10/2021
1	Osteoporosis 04/2021
1	Liver Cirrhosis (Hepatic Cirrhosis) 04/2021
1	von Willebrand Diseases (von Willebrand's Disease) 01/2021
1	Thrombocytosis (Thrombocythemia) 01/2021
1	Sepsis (Septicemia) 01/2021
1	Hematologic Diseases (Blood Diseases) 11/2020
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 01/2020
1	Liver Failure 01/2020
1	Acute Lung Injury 01/2020
1	Hemophilia A (Haemophilia) 01/2020
1	Reticulocytosis 01/2019
1	Hydrops Fetalis (Fetal Edema) 01/2019
1	Congenital Nonspherocytic Hemolytic Anemia (Anemia, Hemolytic Congenital, Nonspherocytic) 01/2018
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2018
1	Stroke (Strokes) 01/2018
1	Gallstones (Gallstone) 01/2018
1	Thalassemia 01/2017
1	Hereditary Elliptocytosis 10/2016
1	Hereditary Pyropoikilocytosis 10/2016

Drug/Important Bio-Agent (IBA)

7	Complement System Proteins (Complement)IBA 01/2022 - 10/2019
5	Pyruvate KinaseIBA 01/2022 - 01/2018
5	Hemoglobins (Hemoglobin)IBA 01/2022 - 01/2017
5	eculizumab FDA Link 01/2022 - 11/2016
4	IsoantibodiesIBA 11/2020 - 11/2018
3	EnzymesIBA 01/2021 - 01/2018
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 10/2016
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 01/2018
2	Monoclonal AntibodiesIBA 01/2022 - 01/2022
2	Isoantigens (Alloantigen)IBA 11/2020 - 01/2018
2	SpectrinIBA 01/2019 - 10/2016
1	mitapivatIBA 01/2022
1	Cephalosporins (Cephalosporin Antibiotics)IBA 01/2022
1	ravulizumabIBA 01/2022
1	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 01/2022
1	Azithromycin (Zithromax)FDA LinkGeneric 01/2022
1	Rituximab (Mabthera)FDA Link 10/2021
1	Alemtuzumab (Campath)FDA Link 10/2021
1	Hydroxyurea (Hydrea)FDA LinkGeneric 01/2021
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Therapeutic UsesIBA 01/2021
1	Immunoglobulin A (IgA)IBA 01/2021
1	HexokinaseIBA 01/2021
1	InterferonsIBA 01/2021
1	Factor VIII (Coagulation Factor VIII)IBA 01/2020
1	IronIBA 01/2019
1	ArtesunateIBA 01/2018
1	Blood Group Antigens (Blood Groups)IBA 01/2018
1	OvalbuminIBA 01/2018
1	Poly I-CIBA 01/2018
1	AntigensIBA 01/2018
1	RNA (Ribonucleic Acid)IBA 01/2018
1	hen egg lysozymeIBA 01/2018
1	Glycophorins (Glycophorin C)IBA 01/2018
1	N- (4'- fluorobutyrophenone)- 4- (4- chlorophenyl)pyridinium (HPP(+))IBA 10/2016

Therapy/Procedure

5	Splenectomy 04/2021 - 01/2018
4	Therapeutics 01/2022 - 01/2018
1	Hematopoietic Stem Cell Transplantation 10/2021
1	Cholecystectomy 04/2021
1	Intrauterine Blood Transfusion 01/2019
1	Blood Transfusion (Blood Transfusions) 01/2018